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Further research, incorporating prospective designs, standardized discontinuations and detailed patient-reported outcomes with validated symptom severity assessment scores, could better elucidate the complex relationship between GLP-1RA use and specific side-effects across IBS subtypesincluding patients who discontinue therapy without switching

They'll determine if a personalized treatment plan is right for you

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This reduces variables that can influence both safety and outcomes compared with self-managed use

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Cahill KN, Amin T, Boutaud O et al (2022) Glucagon-like peptide-1 receptor regulates thromboxane-induced human platelet activation