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This small peptide is eliminated by the kidneys and has a plasma half-life of approximately 3 hours, requiring twice-daily subcutaneous injections

Mutations in GNE result in rare genetic disorders, GNE myopathy and Sialuria

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used a transgenic approach to carry out similar gain- and loss-of-function experiments in the developing mouse cochlea in vivo (Shi et al., 2014)

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