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High-dose carnitine orotate complex (Godex ) intervention for 6 months significantly decreased controlled attenuation parameter (CAP) values in NAFLD patients, indicating reduced hepatic steatosis (39)
At baseline, CV disease and risk factors were managed with lipid-lowering medications (89%), platelet-aggregation inhibitors including aspirin (77%), angiotensin converting enzyme inhibitors or angiotensin II receptor blockers (79%), and beta blockers (64%)
MT-2 activates that pathway effectively
10.1038/nrendo.2012.140 67 MeurotC.MartinC.SudreL.BretonJ.BougaultC.RattenbachR.et al (2022)
Schaumburg et al., Sensory Neuropathy from Pyridoxine Abuse, N
When starting carnitine, as with any supplement, its best to start with a low dose and increase slowly to assess tolerance
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