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Acknowledgements This work was supported by the National Nature Science Foundation of China (82170830), grants from the 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (No

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10.3389/fcell.2022.917575 266 LeinoL.TallT.HelanderM.SaloniemiI.SaikkonenK.RuuskanenS.et al