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M.HouG.JiangH.ChenJ
A major mechanism involves the reduction of intracellular drug accumulation through downregulation of solute carrier (SLC) transporters or upregulation of ATP-binding cassette (ABC) transporters, resulting in decreased drug efficacy
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Safety signals of special interest, including pancreatitis, gallbladder events, neoplasms, and suicidal ideation, were adjudicated by blinded expert committees
doi:10.1038/pcan.2015.32
H.KangJ
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