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The primary structural difference is that Melanotan 1 is a linear peptide that mimics the full length of natural -MSH

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You can protect muscle by getting around 1.2 g of protein per kg of body weight from dals, paneer, curd, soy, and sprouts, and by doing strength work 2 to 4 days a week

Holman RR, Bethel MA, Mentz RJ et al (2017) Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes