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These include the formation and permeability of the BBB, angiogenesis, CBF, the clearance of toxic cellular metabolites, vascular remodeling, and tone, all of which are essential for the normal functioning of the CNS [39]
Human pilot evidence Three small pilots: a 12-patient knee-pain case series (Lee & Padgett, Alternative Therapies in Health and Medicine, 2021)
Starting with 2 mg per week, moving to 4 mg, and then 8 mg weekly for most of the study 5
Guimares ACS1
This mechanism has been studied in the context of wound healing models in rats
Cell Mol Neurobiol 36:203217
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