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Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

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Substances which fall within Section 4.0 of WADAs Technical Document TD2019MRPL (MRPL being an acronym for Minimum Required Performance Levels ), for which the concentrations are merely estimated before determining whether they amount to an adverse analytical finding, by reference to the applicable reporting limits set out in TD2019MRPL

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