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Cellular signaling mechanisms
Indeed, early in vitro studies on rat thyroid follicular cells showed that concurrent treatment with insulin and TSH significantly increased the cell number compared to treatment with TSH alone (Tramontano et al., 1986)
In this context, a focus on weight loss alone is not enough: MNT becomes essential to support treatment outcomes, ensuring nutritional adequacy fundamental to support metabolic health and preserve MM during semaglutide treatment [85]
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