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Patients who are pregnant or breastfeeding, patients with active malignancy, patients with certain vascular conditions where angiogenesis is a concern, and patients on specific anticoagulants may not be candidates
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Estradiol is available, and patches, pills, creams, and pellet form as well
Some studies suggest that combining oral and topical glutathione can provide better brightening results than using either method alone. Certain formulations, such as liposomal or acetylated glutathione, are designed to improve stability and absorption, but clinical outcomes may differ between products
Bull Exp Biol Med 2017;164:413
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